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The Strongest Bond
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Benjamin "Benjy" Stacy so frightened maternity doctors with the color of his skin – “as Blue as Lake Louise” – that he was rushed just hours after his birth in 1975 to University of Kentucky Medical Center.
As a transfusion was being readied, the baby's grandmother suggested to doctors that he looked like the "blue Fugates of Troublesome Creek."
Relatives described the boy's great-
In an unusual story that involves incest, genetics, and geography, an entire family from isolated Appalachia was tinged blue.
Their ancestral line began incest six generations earlier with a French orphan, Martin Fugate, who settled in Eastern Kentucky.
The incestuous Fugate progeny had a genetic condition called methemoglobinemia, which was passed down through a recessive gene and blossomed through intermarriage.
"It's a fascinating story," said Dr. Ayalew Tefferi, a hematologist from Minnesota's Mayo Clinic. "It also exemplifies the intersection between disease and society, and the danger of misinformation and stigmatization."